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Eli Y. Adashi & I. Glenn Cohen, Therapeutic Germline Editing: Sense and Sensibility, 36 Trends in Genetics 315 (2020).

Abstract: Safe and effective heritable editing of the human genome is years away from the clinic because of formidable technical, statutory, regulatory, and societal challenges. In particular, we note the fledgling state of the science, the imperatives of editing efficiency, specificity, and uniformity, and the extant legal roadblock.